4. Celine Dion
Like many others, becoming a mom wasn’t easy for the Canadian singer. When Celine Dion first tried to in her early 30s, she needed one round of IVF to become pregnant with son Rene-Charles, 17. As she and husband Rene Angelil tried again when she was in her 40s, it was even harder. She experienced a miscarriage and went through six rounds of IVF before finally becoming pregnant with her twin sons, Nelson and Eddy, now 7.

Dion is one of the most inspiring stories of celebrities who did IVF. Even though her husband, René Angélil, had children from an earlier marriage, he faced challenges of low sperm count and motility once he was older. At 33, Dion underwent IVF and their first round was successful, leading to the birth of their first son. They were excited to grow their family but, unfortunately, IVF was a larger challenge the second time around. It took six cycles, with miscarriages along the way, but they eventually welcomed twin boys into their family.